Pertuza 420 mg/14 ml
Generic: Pertuzumab
Category: IV Infusion
Manufacturer: Incepta Pharmaceuticals Ltd.
Allopathic
MFG. Licence No. Biological
193
MFG. Licence No. Non-Biological
108
Address
Zirabo, Savar, Dhaka Dewan Idris Road, Bara Rangamatia
Price: 70000.0 ৳
14 ml vial
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Alternative Brands & Related Medicines
Indications
Uses of Pertuza:
- Metastatic breast cancer
- Breast cancer
Therapeutic Class
Targeted Cancer Therapy
Pharmacology
Pertuzumab is a humanized monoclonal antibody designed to bind to the HER2 receptor and inhibit the ability of HER2 to interact with other HER family members (HER1, HER2, HER3, and HER4) on the surface of cancer cells. The HER signaling pathway plays a role in the formation and growth of numerous cancers, and previous clinical trials of pertuzumab in a single agent setting had suggested clinical activity-including stable disease-in heavily pretreated patients with advanced ovarian and breast cancers.
Dosage and Administration
How to use
Pertuzumab:
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Interaction
No drug-drug interactions were observed between pertuzumab and trastuzumab, or between pertuzumab and docetaxel, paclitaxel, or carboplatin.
Contraindications
Pertuzumab is contraindicated in patients with known hypersensitivity to pertuzumab or to any of its excipients
Side Effects
Common
- Diarrhea
- Hair loss
- Feeling sick
- Rash
- Stomach inflammation
- Decreased blood cells (red cells, white cells, and platelets)
- Muscle pain
- Cough
- Heartburn
- Breathlessness
- Dizziness
- Fatigue
Pregnancy And Lactation
Females and Males of Reproductive Potential: Verify the pregnancy status of females prior to initiation of Pertuzumab. There is no information regarding the presence of pertuzumab in human milk, the effects on the breastfed infant or the effects on milk production.
Precautions And Warnings
Infusion-Related Reactions: Monitor for signs and symptoms. If a significant infusion-associated reaction occurs, slow or interrupt the infusion and administer appropriate medical therapies.Hypersensitivity Reactions/Anaphylaxis: Monitor for signs and symptoms. If a severe hypersensitivity reaction/anaphylaxis occurs, discontinue the infusion immediately and administer appropriate medical therapies
Storage Conditions
Store vials in a refrigerator at 2°C to 8°C until time of use. Keep vial in the outer carton in order to protect from light.
Drug Classes
Targeted Cancer Therapy
Mode of Action
Pertuzumab is a humanized monoclonal antibody designed to bind to the HER2 receptor and inhibit the ability of HER2 to interact with other HER family members (HER1, HER2, HER3, and HER4) on the surface of cancer cells. The HER signaling pathway plays a role in the formation and growth of numerous cancers, and previous clinical trials of pertuzumab in a single agent setting had suggested clinical activity-including stable disease-in heavily pretreated patients with advanced ovarian and breast cancers.
Pregnancy Category
Females and Males of Reproductive Potential: Verify the pregnancy status of females prior to initiation of Pertuzumab. There is no information regarding the presence of pertuzumab in human milk, the effects on the breastfed infant or the effects on milk production.
Samm Care