Natrilex 1.5 mg Tablet - Price, Uses, Dosage, Side Effects ( Indapamide)

Q: What are the indications for Natrilex?

Uses of Indapamide: - Hypertension (high blood pressure) Hypertension, Congestive heart failure Anuria, severe hepatic impairment.

Indications

Uses of Natrilex: - Hypertension (high blood pressure) Hypertension, Congestive heart failure Anuria, severe hepatic impairment.

Therapeutic Class

Thiazide diuretics & related drugs

Pharmacology

Indapamide is a diuretic antihypertensive. It appears to cause vasodilation, probably by inhibiting the passage of calcium and other ions (sodium, potassium) across membranes. It has an extra-renal antihypertensive action resulting in a decrease in vascular hyperreactivity and a reduction in total peripheral and arteriolar resistance.

Dosage and Administration

How to use Indapamide: Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Indapamide may be taken with or without food, but it is better to take it at a fixed time. Administration: Should be taken with food. Adult Dose: Oral Hypertension Adult: 1.25-2.5 mg once daily, alone or in conjunction with other antihypertensives. Oedema Adult: 2.5 mg once daily increased to 5 mg daily after 1 wk if needed. Child Dose: Safety & efficacy not established

Interaction

Additive effect with other antihypertensive agents and diuretics. Increased chance of hypokalaemia with corticosteroids, corticotropin and amphotericin. Potentially Fatal: Increased risk of lithium toxicity. Hypokalaemia enhances digitalis toxicity with cardiac gycosides.

Contraindications

Anuria, severe hepatic impairment.

Side Effects

Common - Dizziness - Headache - Fatigue - Nausea - Gastrointesinal symptoms - Muscle cramp 1-10% Hypotension,Palpation,Flushing,Dizziness,Lightheadedness,Vertigo,Headache,Weakness,Restlessness,Drowsiness,Fatigue,Lethargy,Malaise,Anorexia,Nausea/vomiting,Nocturia,Polyuria,Blurred vision,Rhinnorhea,Electrolyte abnormalities,Pruritus,Rash <1% Cutaneous vasculitis,Glycosuria,Pancreatitis

Pregnancy And Lactation

There are no adequate and well-controlled studies in pregnant women and so Indapamide is not recommended. Mothers taking Indapamide should not breast feed.

Precautions And Warnings

Precaution: Pregnancy, lactation, elderly, renal impairment, fluid or electrolyte imbalance, hyperuricaemia, DM, lupus erythematosus. Lactation: not known if excreted into breast milk, avoid

Overdose Effects

Symptoms: These could include: allergies, skin rashes, epigastric pain, nausea, photosensitivity, dizziness, weakness and paraesthesia.Treatment: Treatment is supportive and symptomatic, directed at correcting the electrolyte abnormalities.

Storage Conditions

Store in a cool and dry place. Protect from light and moisture.

Drug Classes