Melato tablet 3 mg
Generic: Melatonin
Category: Tablet
Manufacturer: Beximco Pharmaceuticals Ltd.
Allopathic
MFG. Licence No. Biological
119
MFG. Licence No. Non-Biological
379
Address
Tongi I/A, Gazipur
Price: 3.0 ৳
1 x 10 in Blister Pack
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Alternative Brands & Related Medicines
Indications
Uses of Melato tablet:
- Insomnia
- Jet lag
Disturbed biorhythms, Sleep disorders, Insomnia, Osteoporosis, In menopause to regulate sleep patterns in peri or postmenopausal women, To correct the symptoms of anorexia, Attention Deficit Hyperactivity Disorder in Children,
Pregnancy and lactation.
Therapeutic Class
Hormone preparations for other uses, Oral nutritional preparations
Pharmacology
Melatonin and melatonin agonists inhibit the release of dopamine from retina through activation of a site that is pharmacologically different from a serotonin receptor. These inhibitory effects are antagonized by the melatonin receptor antagonist luzindole, which suggests that melatonin activates a presynaptic melatonin receptor.
Dosage and Administration
How to use
Melatonin:
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it.
Melatonin is to be taken empty stomach.
Adult Dose:
Oral
Disturbed biorhythms; Sleep disorders
Adult: Usual dose 3-6 mg at bedtime.
Child Dose:
Oral
Disturbed biorhythms; Sleep disorders
Child: 2-3 mg at bedtime, increased after 1-2 wk to 4-6 mg if needed.
Max dose 10 mg.
Interaction
Quinolones; carbamazepine, rifampicin; fluvoxamine, 5- or 8-methoxypsoralen, cimetidine, cigarette smoking, oestrogens. Alcohol; zalepon, zolpidem, zopiclone; thioridazine, imipramine.
Contraindications
Pregnancy and lactation.
Side Effects
Common
- Headache
- Drowsiness
Increased seizure activity; drowsiness, headache. Disruption of normal circadian rhythm. May worsen symptoms for individuals with depression.
Pregnancy And Lactation
Information regarding safety and efficacy in pregnancy and lactation is not available.
Precautions And Warnings
Precaution:
May impair ability to drive or operate machinery. Epilepsy
Overdose Effects
There is little or no evidence of any major toxicities with melatonin,even at high doses.
Storage Conditions
Store below 30°C. Keep away from light. Keep all the medicine out of reach of children.
Drug Classes
Hormone preparations for other uses, Oral nutritional preparations
Mode of Action
Melatonin is the hormone secreted by the pineal gland. In humans, the plasma levels of melatonin are high at night and low during the day and it appears to have a role in circardian rhythm regulation.
Pregnancy Category
Information regarding safety and efficacy in pregnancy and lactation is not available.
Samm Care