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    Laxefin 1.25 ml + 300 mg/5 ml Suspension

    Laxefin 1.25 ml + 300 mg/5 ml

    Generic: Liquid Paraffin + Magnesium Hydroxide

    Category: Suspension

    Manufacturer: Sharif Pharmaceuticals Ltd.

    Price: 95.29 ৳

    100 ml in Bottle

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    Indications

    Constipation Renal failure, existing electrolyte imbalance, appendicitis symptoms, acute surgical abdomen, myocardial damage, heart block, fecal impaction, rectal fissures, intestinal obstruction or perforation, pregnant, bedridden, dysphagia

    Dosage and Administration

    Administration: The dose may be mixed with milk or half a glass of water if desired. Adult Dose: Oral Adults: Constipation The recommended oral dose are as follows- 15-30ml before breakfast and/or at bedtime. Up to 45 mL/day. Max duration: 1 wk. Child Dose: Oral Children: Constipation Over 7 years: 7.5ml-15ml at bedtime. 3-7 years: 5-10ml at bedtime.

    Interaction

    May impair absorption of fat-soluble vitamins and possibly other compounds.

    Contraindications

    Renal failure, existing electrolyte imbalance, appendicitis symptoms, acute surgical abdomen, myocardial damage, heart block, fecal impaction, rectal fissures, intestinal obstruction or perforation, pregnant, bedridden, dysphagia

    Side Effects

    Anal irritation (excessive dose) and seepage. Foreign-body granulomatous reactions; vasospasm; lipoid pneumonia; interference with absorption of fat-soluble vitamins. Hypotension, electrolyte imbalance, abdominal pain, nausea and vomiting may present.

    Precautions And Warnings

    Precaution: Oral: not recommended for use in patients with difficulty swallowing or impaired neurodevelopment. Avoid prolonged use as a laxative or faecal softener.

    Mode of Action

    Paraffin: When taken orally: penetrates and softens faecal material. Magnesium hydroxide increases peristaltic activity causing osmotic retention of fluids, thus resulting in bowel evacuation. It also reduces stomach acid by reacting with hydrochloric acid to form Mg chloride.
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