Gat 500 mg Tablet - Price, Uses, Dosage, Side Effects ( Ornidazole)

Indications

Uses of Gat: - Bacterial & parasitic infections

Therapeutic Class

Amoebicides, Anti-diarrhoeal Antiprotozoal

Pharmacology

Ornidazole is a 5-nitroimidazole derivative active against protozoa and anaerobic bacteria. It is converted to reduction products that interact with DNA to cause destruction of helical DNA structure and strand leading to a protein synthesis inhibition and cell death in susceptible organisms.

Dosage and Administration

How to use Ornidazole: Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ornidazole is to be taken with food.

Interaction

Like other imidazoles, Ornidazole has a mild potential to cause disulfiramlike reactions. Concomitant administration of oral anticoagulants may increase the risk of haemorrhage due to diminished hepatic metabolism. Ornidazole has been reported to decrease the clearance of 5-fluorouracil.

Contraindications

Previous hypersensitivity to Ornidazole and to other nitroimidazoles. Ornidazole is contraindicated in central nervous system disorders, particularly in epilepsy or in peripheral neuropathy.

Side Effects

Common - Dizziness - Headache - Nausea - Numbness of extremity - Skin reaction - Sleepiness - Tiredness - Tremor - Vertigo - Vomiting

Pregnancy And Lactation

Adequate clinical trials have not been conducted. Ornidazole should be prescribed only if the potential benefit justifies the potential risk to fetus/neonate.

Precautions And Warnings

In patient with ataxia, vertigo, and mental confusion, Ornidazole should be prescribed with caution. During prolonged treatment with Ornidazole, blood dyscrasia namely mild leukopenia have been reported rarely. In case leukopenia occurs, the decision to discontinue the therapy should depend upon the gravity of infection.

Storage Conditions

Store at room temperature and protect from light and moisture.

Drug Classes