Gabahil 100 100 mg Tablet

    Gabahil 100 100 mg

    Generic: Gabapentin

    Category: Tablet

    Manufacturer: Goodman Pharmaceuticals Ltd.

    Price: 6.0

    1 x 10 in Blister Pack

    Indications

    Gabahil 100 is indicated for- Neuropathic Pain. Adjunctive therapy in partial seizure and secondary generalized seizure.

    Therapeutic Class

    Adjunct anti-epileptic drugs

    Pharmacology

    Gabapentin is an anti-convulsant. It is a structural analog of gamma-amino-butyric-acid (GABA). All pharmacological actions following administration of Gabapentin are due to the activity of parent compound. Gabapentin binds with the alpha-2-delta subunit of voltage gated L-type Calcium channel, and inhibits branched chain amino acid transferase & probably inhibits neurotransmitter release of excitatory amino acid.

    Interaction

    Antacids may reduce the bioavailability of Gabapentin by up to 20 %. Cimetidine may alter its reanal excretion. Gabapentin does not interact with other anti-epileptic drug or with oral contraceptive preparations.

    Contraindications

    Gabapentin is contraindicated in patients who have known hypersensitivity to the drug.

    Side Effects

    Fatigue, Dizziness, ataxia, weight gain, peripheral edema, dry mouth and somnolence may occur.

    Pregnancy And Lactation

    Pregnancy category C. it should be used during pregnancy only if potential benefits justifies the potential risk to the fetus. Gabapentin may be secreted through the breast milk. So it should be used during lactation only if potential benefits justifies the potential risk to the baby.

    Precautions And Warnings

    Patients should be instructed to take Gabapentin only as prescribed. While using Gabapentin patients should be instructed either not to drive a car or to operate other complex machinery until they have gained sufficient experiences about Gabapentin whether or not it affects their mental and/or motor performance adversely.

    Storage Conditions

    Store below 25°C temperature. Protect from light and moisture. Keep all the medicines out of the reach of the children.

    Drug Classes

    Adjunct anti-epileptic drugs

    Mode of Action

    Gabapentin is an anti-convulsant. It is a structural analog of gamma-amino-butyric-acid (GABA). All pharmacological actions following administration of Gabapentin are due to the activity of parent compound. Gabapentin binds with the alpha-2-delta subunit of voltage gated L-type Calcium channel, and inhibits branched chain amino acid transferase & probably inhibits neurotransmitter release of excitatory amino acid.

    Pregnancy Category

    Pregnancy category C. it should be used during pregnancy only if potential benefits justifies the potential risk to the fetus. Gabapentin may be secreted through the breast milk. So it should be used during lactation only if potential benefits justifies the potential risk to the baby.
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