Elo 10 mg
Generic: Loratadine
Category: Tablet
Manufacturer: Edruc Ltd.
Allopathic
MFG. Licence No. Biological
018
MFG. Licence No. Non-Biological
018
Address
Pabna
Price: 2.25 ৳
Tablet
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Alternative Brands & Related Medicines
Indications
Uses of Elo:
- Allergic conditions
Therapeutic Class
Non-sedating antihistamines
Pharmacology
Loratadine is a tricyclic antihistamine with selective peripheral histamine H1-receptor antagonistic activity. It is devoid of anticholinergic activity. It is rapidly effective and long-lasting, allowing once-a-day administration.
Dosage and Administration
How to use
Loratadine:
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it.
Loratadine is to be taken empty stomach.
Interaction
There are no reports of potentially hazardous interactions with other drugs. In contrast to many other histamine H1 receptor antagonists, Loratadine has no potentiating effects when administered concurrently with alcohol, as measured by psychomotor performance studies. Concomitant therapy with drugs that inhibit or are metabolized by hepatic cytochromes P450 3A4 and 2D6 may elevate plasma concentrations of either drug and this mayifesult in adverse effects. Cimetidine inhibits both enzymes while erythromycin or ketoconazole inhibits P450 3A4. These drugs increase loratadine serum concentrations but no adverse effects are reported.
Contraindications
Loratadine is contraindicated in patients who have shown hypersensitivity or idiosyncrasy to their components.
Side Effects
Common
- Sleepiness
- Increased appetite
Pregnancy And Lactation
US FDA Pregnancy Category of Loratadine is B. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. Loratadine have been shown to be excreted in human milk. So, caution should be exercised when Loratadine is administered to a nursing woman.
Precautions And Warnings
Caution should be taken in patients with liver impairment or renal insufficiency (eGFR <30 ml/min).
Overdose Effects
In adults somnolence, tachycardia and headache have been reported with overdose greater than 10 mg. Extrapyramidal signs and palpitations have been reported in children with overdoses of greater than 10 mg. In the event of overdosage, general symptomatic and supportive measures should be instituted promptly and maintained for as long as necessary. It would seem reasonable to treat patients presenting early after large overdoses with oral activated charcoal. The conscious patients may be induced to vomit or gastric lavage may be performed.
Storage Conditions
Keep in a dry place away from light and heat. Keep out of the reach of children.
Drug Classes
Non-sedating antihistamines
Mode of Action
This tablet is a preparation of Loratadine. Loratadine is a non-sedative histamine Hr receptor antagonist with antiallergic properties. Loratadine is a long-acting tricyclic antihistamine with selective peripheral Hi-receptor antagonistic activity and no central sedative or anticholinergic effect. It is rapidly effective and long-lasting, allowing once-a-day administration.
Pregnancy Category
There is no experience of the use of Loratadine in human pregnancy. Therefore its use during pregnancy is not advisable. Loratadine is excreted in breast milk in a very small amount. So nursing mothers are advised not to take the drug.
Samm Care