Duvent 100 mg/100 ml
Generic: Rupatadine
Category: Oral Solution
Manufacturer: Beximco Pharmaceuticals Ltd.
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Allopathic
MFG. Licence No. Biological
119
MFG. Licence No. Non-Biological
379
Address
Tongi I/A, Gazipur
Alternative Brands & Related Medicines
Indications
Allergic rhinitis, Chronic idiopathic urticaria
Dosage and Administration
Adult Dose
Oral
Allergic rhinitis; Chronic idiopathic urticaria
Adult: 10 mg (1 tablet) once daily.
Child Dose
Oral
Allergic rhinitis; Chronic idiopathic urticaria
Tablet
Child > 12 years: 10 mg (1 tablet) once daily.
Children: Use of Rupatadine is not recommended in patients less than 12 years of age.
Syrup:
Children aged 2 to 11 years:
Children weighing 10 kg to less than 25 kg: 1/2 teaspoonful (2.5 ml) syrup once a day with or without food.
Children weighing 25 kg or more: 1 teaspoonful (5ml) of syrup once a day with or without food.
Interaction
Increased CNS depressant effects when used with CNS depressants or alcohol.
Contraindications
Hypersensitivity. Avoid alcohol.
Side Effects
Headache, somnolence, fatigue/asthenia.
Precautions And Warnings
Renal or hepatic insufficiency. May impair ability to drive or operate machinery. Pregnancy, lactation. Elderly, children <12 yr.
Mode of Action
Rupatadine acts as a long-acting, non-sedative antagonist at histaminergic H1-receptors. Rupatadine also antagonises the platelet-activating factor (PAF). Both histamine and PAF cause bronchoconstriction and lead to an increase in the vascular permeability, acting as mediators in the inflammatory process.
Samm Care