D-Siblin

Uses of D-Siblin : D-Siblin use as a laxatives. Constipation - Raised levels of cholesterol - Hemorrhoids or piles - Irritable bowel syndrome (IBS) - Reduces blood glucose level. Contraindicated in patients with gastrointestinal tract obstruction or threatening obstruction of the bowel.

Bulk-forming laxatives

Most of the Ispaghula reach the caecum within four hours after ingestion in an intact and highly polymerized form. Ispaghula husk significantly increases the level of stool moisture, as well as wet and dry stool weight and shorten gastrointestinal transit time. Anaerobic fermentation of the soluble non-starch polysaccharides from Ispaghula seed results in the production of short chain fatty acids, acetate, propionate and butyrate in the intestine. Butyric acid is the preferred oxidative substrate for colonocytes and may be helpful in the treatment of ulcerative colitis. Ispaghula has hypocholesterolemic effects also. It is assumed that Ispaghula increases the activity of cholesterol alpha hydroxylase, HMG-CoA reductase and fractional turnover of both chenodeoxycholic and cholic acids. As a result it decreases cholesterol absorption and lowers LDL cholesterol.

How to use Ispaghula Husk: Ispaghula Husk take orally with plenty of water. Administration: Its Usually typically administered orally in the form of powder or granules. The powder or granules are mixed with water and consumed once or twice per day .It is important to take ispaghula husk with plenty of fluids, as it can cause dehydration if not taken with enough water. Adult Dose: Adults and children over 12 years: 1 spoonful with water 2 times daily or as per doctor’s advice. Child Dose: Children 6 to 12 years: ½ to 1 spoonful with water depending on age and weight. Renal Dose: It is generally considered safe for use in people with renal disease. Patients with kidney disease, should be consult with doctor before using it.

No significant interaction has been observed with other medicine.

Contraindicated in patients with gastrointestinal tract obstruction or threatening obstruction of the bowel.

- Abdominal pain - Bloating - Diarrhea - Stomach irritation - Intestinal obstruction Flatulence, abdominal distension, gastro-intestinal obstruction.

Pregnancy & Lactation Category Note: Generally this should not be used during pregnancy . However, it is important to talk with doctor before taking it. Lactation :It does not pass through breast milk. As a result, it can be safely used during lactation.

Precaution: Consuming dried husk orally without water may cause problems.

Symptoms: Abdominal discomfort and flatulence. Management: Maintain adequate fluid intake.

Store in a cool and dry place. Keep out of reach of children.

Ispaghula husk absorbs water in the intestines, increasing stool bulk and promoting bowel movements. This helps relieve constipation and promote regularity. This increased fiber intake also contributes to cholesterol reduction by reducing the absorption of dietary cholesterol.