Calate 300 mg Tablet

    Calate 300 mg

    Generic: Calcium Lactate

    Category: Tablet

    Manufacturer: Pharmadesh Laboratories Ltd.

    Price: 0.47

    Tablet

    Indications

    Heartburn, Calcium supplement, Calcium deficiencies Conditions associated with hypercalcaemia and hypercalciuria.

    Therapeutic Class

    Minerals in bone formation, Specific mineral preparations

    Pharmacology

    Calcium is used to prevent or treat negative calcium balance. It also helps facilitate nerve and muscle performance as well as normal cardiac function. Bone mineral component; cofoactor in enzymatic reactions, essential for neurotransmission, muscle contraction, and many signal transduction pathways.

    Dosage and Administration

    Administration: Should be taken with food. Adult Dose: Adult: PO 19-50 yr: 1,000 mg elemental Ca/day and >50 yr: 1,200 mg elemental Ca/day. Renal Dose: Renal impairment (frequent monitoring of serum calcium and phosphorus is recommended);

    Interaction

    May reduce the efficacy of calcium-channel blockers. Concurrent admin of IV calcium salt with cardiac glycosides may lead to serious adverse events. Increased risk of hypercalcaemia when used with thiazide diuretics. May reduce absorption of tetracycline, alendronate, atenolol, iron, quinolone antibiotics, sodium fluoride and zinc.

    Contraindications

    Conditions associated with hypercalcaemia and hypercalciuria.

    Side Effects

    GI discomfort e.g. nausea, vomiting, constipation; bradycardia, arrhythmias. Dry mouth, increased thirst or increased urination. Mental confusion, milk-alkali syndrome.

    Pregnancy And Lactation

    Pregnancy Category-C. Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

    Precautions And Warnings

    Precaution: Sarcoidosis; history of nephrolithiasis. Avoid IV admin of calcium in patients on cardiac glycosides. Increased risk of hypercalcaemia and hypercalciuria in hypoparathyroid patients receiving high doses of vitamin D. Caution when used in patients with history of kidney stones. Patients should be advised to administer vitamin D concurrently to optimise calcium absorption. Pregnancy.

    Drug Classes

    Minerals in bone formation, Specific mineral preparations

    Mode of Action

    Calcium is used to prevent or treat negative calcium balance. It also helps facilitate nerve and muscle performance as well as normal cardiac function. Bone mineral component; cofoactor in enzymatic reactions, essential for neurotransmission, muscle contraction, and many signal transduction pathways.

    Pregnancy Category

    Pregnancy Category-C. Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks
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