Aexidal 50 mg Tablet

    Aexidal 50 mg

    Generic: Mebhydrolin

    Category: Tablet

    Manufacturer: Albion Laboratories Ltd.

    Price: 1.8

    Tablet

    Indications

    Allergic conditions Premature infants and neonates. Acute asthmatic attack.

    Dosage and Administration

    Administration: Should be taken with food. Take during or shortly after meals. Adult Dose: Oral Allergic conditions Adult: 100-300 mg/day. Child Dose: Oral Allergic conditions Child: <2 yr: 50-100 mg/day; 2-5 yr: 50-150 mg/day; 5-10 yr: 100-200 mg/day; >10 yr: 100-300 mg/day.

    Interaction

    Enhanced sedation with alcohol or other CNS depressants. Additive antimuscarinic effects with MAOIs, atropine, TCAs. May mask warning symptoms caused by ototoxic agents e.g. aminoglycoside antibiotics.

    Contraindications

    Premature infants and neonates. Acute asthmatic attack.

    Side Effects

    CNS depression; paradoxical stimulation (high doses, children or elderly); headache, psychomotor impairment; dry mouth, thickened respiratory tract secretions, blurred vision; urinary difficulty or retention, constipation, increased gastric reflux; nausea, vomiting, diarrhoea, epigastric pain. Rarely, blood disorders. Convulsions, sweating, myalgia, paraesthesias, extrapyramidal effects, tremor, sleep disturbances, depression, confusion, tinnitus, hypotension, hair loss. Potentially Fatal: Anaphylaxis.

    Precautions And Warnings

    Precaution: Closed-angle glaucoma; urinary retention, prostatic hyperplasia or pyloroduodenal obstruction; epilepsy. Elderly. Pregnancy. May impair ability to drive or operate machinery.

    Mode of Action

    Mebhydrolin is an ethylenediamine derivative antihistamine with antimuscarinic and sedative properties.
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