Advasol Powder (Vet) 30 % Powder

    Advasol Powder (Vet) 30 %

    Generic: Levamisole

    Category: Powder

    Manufacturer: Adova Pharmaceuticals Ltd.

    Price: 150.0

    100 gm Sachets

    Indications

    Uses of Advasol Powder (Vet): - Worm infections Ascariasis, Ancylostomiasis Preexisting blood disorders; pregnancy and lactation; rheumatoid arthritis; severe renal impairment.

    Therapeutic Class

    Anthelmintic

    Pharmacology

    Levamisole is the active laevo-isomer of tetramisole. It works by paralysing susceptible intestinal worms which are then excreted from the intestines. Levamisole also enhances cellular immune responses in humans.

    Dosage and Administration

    How to use Levamisole: Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Levamisole is to be taken with food. Administration: Should be taken with food. Take w/ meals to minimise side effects eg nausea. Adult Dose: Oral Ascariasis Adult: 150 mg as a single dose. Mixed ascariasis-hookworm infections; Ancylostomiasis Adult: 2.5 mg/kg as a single dose, repeated after 7 days in severe cases. Child Dose: Oral Ascariasis Child: 3 mg/kg as a single dose. Mixed ascariasis-hookworm infections; Ancylostomiasis Child: 2.5 mg/kg as a single dose, repeated after 7 days in severe cases.

    Interaction

    May increase toxicity of phenytoin. Increases bioavailability of ivermectin; decreases bioavailability of albendazole. Alcohol causes disulfiram-like reaction.

    Contraindications

    Preexisting blood disorders; pregnancy and lactation; rheumatoid arthritis; severe renal impairment.

    Side Effects

    Common - Vomiting - Headache - Dizziness - Nausea - Abdominal pain Nausea, vomiting, diarrhoea, abdominal pain, dizziness and headache. Fever, influenza-like syndrome, arthralgia, muscle pain, rash, taste disturbances and cutaneous vasculitis. Potentially Fatal: Agranulocytosis, leucopenia, thrombocytopenia.

    Pregnancy And Lactation

    Although studies in animals have shown that Levamisole produces no teratogenic effects, current medical practice requires that the benefits of any drug used during pregnancy should be weighed against the possible dangers.

    Precautions And Warnings

    Precaution: Hepatic impairment, Sjogren's syndrome.

    Overdose Effects

    Counter possible anticholinesterase activity with e.g. atropine. Control blood pressure and respiration . Do not use sedatives.

    Storage Conditions

    Tablet: Store in room temperature and protect from moisture.Syrup: Store in room temperature and protect from light.

    Drug Classes

    Anthelmintic

    Mode of Action

    Levamisole is the active laevo-isomer of tetramisole. It works by paralysing susceptible intestinal worms which are then excreted from the intestines. Levamisole also enhances cellular immune responses in humans.

    Pregnancy Category

    Although studies in animals have shown that Levamisole produces no teratogenic effects, current medical practice requires that the benefits of any drug used during pregnancy should be weighed against the possible dangers.
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