Acme's Milk Of Magnesium 400 mg/5 ml Suspension - Price, Uses, Dosage, Side Effects ( Magnesium Hydroxide)

Indications

Heartburn, Constipation, Indigestion, Gastrointestinal hyperacidity, Osmotic laxative Intestinal obstruction, faecal impaction; renal failure; appendicitis.

Therapeutic Class

Antacid with laxative action

Pharmacology

Magnesium Hydroxide is popularly known as Milk of Magnesia. It is a mildly acting antacid and laxative. It is poorly and slowly absorbed and acts by its osmotic properties in the luminal fluid which causes retention of fluid in the bowel. It is useful for emptying the bowel prior to surgical, radiological and colonoscopic procedures and can help to eliminate parasites following appropriate therapy and toxic material in some cases of poisoning. Magnesium Hydroxide is converted into Magnesium Chloride in the stomach without forming carbon dioxide

Dosage and Administration

Adult Dose: Constipation Magnesium hydroxide (400 mg/5 mL): 30-60 mL/day PO at bedtime or in divided doses Acid Indigestion Magnesium hydroxide (400 mg/5 mL): 5-15 mL PO q4hr; no more than 4 doses per 24-hour period Child Dose: Constipation <2 years: Safety and efficacy not established Suspension 2-6 years: 5-15 mL/day of regular-strength liquid PO at bedtime or in divided doses 6-12 years: 15-30 mL/day (400 mg/5 mL) >12 years: 30-60 mL/day (400 mg/5 mL) Acid Indigestion Liquid <12 years: Not recommended >12 years: 5-15 mL (400 mg/5 mL) PO q4hr; no more than 4 doses per 24-hour period

Interaction

Decreases absorption of tetracyclines and biphosphonates. Separate administration of these and other drugs by around 2 hr.

Contraindications

Intestinal obstruction, faecal impaction; renal failure; appendicitis.

Side Effects

Abdominal cramping, Diarrhea, Electrolyte imbalance, Hypotension, Muscle weakness, Respiratory depression, Hypermagnesaemia (in patients with renal impairment). Paralytic ileus.

Precautions And Warnings

Precaution: Colostomy, ileostomy; electrolyte imbalance. Monitor for toxicity in patients with impaired renal function. Pregnancy. Lactation: Use in nursing mothers appears to be safe

Storage Conditions

Store in a cool & dry place, protected from light. Keep all medicines out of reach of children.

Drug Classes

Antacid with laxative action

Mode of Action

Magnesium hydroxide increases peristaltic activity causing osmotic retention of fluids, thus resulting in bowel evacuation. It also reduces stomach acid by reacting with hydrochloric acid to form Mg chloride.

Acme's Milk Of Magnesium 400 mg/5 ml

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