Uses of Acidrox Plus:
- Acidity
- Stomach ulcers
- Bloating
Heartburn, Hyperacidity, Indigestion, Dyspepsia, Gastritis, Peptic ulcers, GERD
Magaldrate is contraindicated in patients with known hypersensitivity to magnesium and aluminium. It is also contraindicated in patients with impaired renal functions.
Therapeutic Class
Antacids, Anti-dyspeptic/Carminatives
Pharmacology
Magaldrate neutralizes gastric acid, thereby increasing pH of stomach and duodenal bulb. It also increases lower esophageal sphincter tone and inhibits smooth muscle contraction and gastric emptying. Simethicone lowers the surface tension of gas bubbles.
Dosage and Administration
How to use
Magaldrate + Simethicone:
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use.
Magaldrate + Simethicone is to be taken with food.
Administration:
Take between meals & at bedtime.
Adult Dose:
Oral
Adult:
Suspension: 2-4 teaspoonful orally 3-4 times daily after 20-60 minutes of meals and at bedtime.
Child Dose:
Children 12 years and older:
Suspension: 2-4 teaspoonful orally 3-4 times daily after 20-60 minutes of meals and at bedtime.
Interaction
Magaldrate may negatively influence drugs like tetracyclines, benzodiazepines, and indomethacin. High doses or prolonged usage may lead to an increment of defecation and a reduction in feces consistence. In some cases it can alter the functionality of the gastrointestinal tract, occasionally provoking constipation or diarrhea.
Contraindications
Magaldrate is contraindicated in patients with known hypersensitivity to magnesium and aluminium. It is also contraindicated in patients with impaired renal functions.
Pregnancy category C. So should be used in pregnancy only when necessary. Chronic high dose should be avoided.
Precautions And Warnings
Precaution:
Care should be taken in decreased kidney function, hypophosphataemia and weak people.
Overdose Effects
Over dosage with this formulation is a rare case.
Storage Conditions
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
Drug Classes
Antacids, Anti-dyspeptic/Carminatives
Mode of Action
Magaldrate is a hydroxymagnesium aluminate complex that is rapidly converted in gastric acid to magnesium and aluminium hydroxide, which is poorly absorbed and provides a sustained antacid effect with balanced efects on intestinal motility; increases lower esophageal sphincter tone and inhibits smooth muscle contraction and gastric emptying.
Simethicone allows gas bubbles in the stomach and intestines to come together more easily, which allows for easier passage of gas.
Pregnancy Category
Magaldrate may be used in pregnancy if indicated however one should avoid excessive dosage. Magaldrate may pass into breast milk but has not been reported to cause problem in nursing babies.
